Please read Dr. Jimenez’s article in the Journal of Clinical and Translational Science titled, “The application of quality improvement concepts, strategies, and tools to enhance participation in clinical trials among Latino families.“
People from Latino backgrounds are now the second largest ethnic group in the USA. In 2021, children from Latino backgrounds represented 26% of US children compared to 14% in 1993. Despite these trends, between 2007 and 2020, the median proportion of Latino children participating in clinical trials was just 7%, compared to 66% for White children.
Efforts to increase participation in clinical trials among people from minoritized groups and enhance reporting span decades. For example, the Revitalization Act of 1993 sought to ensure that National Institutes of Health (NIH)-funded research included data on gender and race/ethnicity and examined differential effects between groups. In 2016, the 21st Century Cures Act required applicable clinical trials to submit results of valid analyses by gender, race, and ethnicity to ClinicalTrials.gov. More recently, the National Institute on Minority Health and Health Disparities strategic plan included major goals focused on enhancing diversity and inclusion in NIH-funded research and clinical trials. Despite existing efforts, reporting remains inconsistent, and representation of people from minoritized groups in clinical trials is not reflective of recent demographic shifts. In an analysis of 20,000 studies from 2000 to 2020, 43% of studies reported race/ethnicity data, and among those that did, people from racial and ethnic minoritized groups remained underrepresented. To read the full article.
The application of quality improvement concepts, strategies, and tools to enhance participation in clinical trials among Latino families. Malke K, Hemler JR, Lima D, Colon P, Mendoza C, Azcona N, Devine KA, Mackie TI, Ramachandran U, Forbes D, Lucas M, Hudson SV, Jimenez, ME. Journal of Clinical and Translational Science. 2024; 8(1):e146. DOI:1017/cts.2024.557