2020 Publications
- FFAR1 activation attenuates histamine-induced myosin light chain phosphorylation and cortical tension development in human airway smooth muscle cells Xu S, Schwab A, Karmacharya N, Cao G, Woo J, Kim N, An SS, Panettieri RA Jr, Jude JA. . Respir Res. 2020 Nov 30;21(1):317.
- In-Hospital Mortality and Prediction in an Urban U.S. Population With COVID-19. Rustgi V, Makar M, Minacapelli CD, Gupta K, Bhurwal A, Li Y, Catalano C, Panettieri R. Cureus. 2020 Nov 30;12(11):e11786. doi: 10.7759/cureus.11786. PMID: 33409033.
- Airway relaxation mechanisms and structural basis of osthole for improving lung function in asthma. Wang S, Xie Y, Huo YW, Li Y, Abel PW, Jiang H, Zou X, Jiao HZ, Kuang X, Wolff DW, Huang YG, Casale TB, Panettieri RA Jr, Wei T, Cao Z, Tu Y. Sci Signal. 2020 Nov 24;13(659):eaax0273. doi: 10.1126/scisignal.aax0273. PMID: 33234690.
- Prevalence of SARS-CoV-2 infection in previously undiagnosed health care workers in New Jersey, at the onset of the U.S. COVID-19 pandemic. Barrett ES, Horton DB, Roy J, Gennaro ML, Brooks A, Tischfield J, Greenberg P, Andrews T, Jagpal S, Reilly N, Carson JL, Blaser MJ, Panettieri RA Jr. BMC Infect Dis. 2020 Nov 16;20(1):853. doi: 10.1186/s12879-020-05587-2. PMID: 33198725.
- The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR. Huang J, Lam H, Koziol-White C, Limjunyawong N, Kim D, Kim N, Karmacharya N, Rajkumar P, Firer D, Dalesio NM, Jude J, Kurten RC, Pluznick JL, Deshpande DA, Penn RB, Liggett SB, Panettieri RA Jr, Dong X, An SS. Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28485-28495. doi: 10.1073/pnas.2003111117. Epub 2020 Oct 23. PMID: 33097666.
- Risk Factors for Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Hospital Workers: Results From a Screening Study in New Jersey, United States in Spring 2020 Barrett ES, Horton DB, Roy J, Xia W, Greenberg P, Andrews T, Gennaro ML, Parmar V, Russell WD, Reilly N, Uprety P, Gantner JJ, Stockman L, Trooskin SZ, Blaser MJ, Carson JL, Panettieri RA Jr. Open Forum Infect Dis. 2020 Oct 31;7(12):ofaa534. eCollection 2020 Dec.
- Dexamethasone rescues TGF-β1-mediated β2-adrenergic receptor dysfunction and attenuates phosphodiesterase 4D expression in human airway smooth muscle cells Chung E, Ojiaku CA, Cao G, Parikh V, Deeney B, Xu S, Wang S, Panettieri RA Jr, Koziol-White CJ. Respir Res. 2020 Oct 8;21(1):256. doi: 10.1186/s12931-020-01522-w. PMID: 33032603.
- Asthma and COVID: What Are the Important Questions? Panettieri RA Jr, Carson J, Horton D, Barrett E, Roy J, Radbel J. J Allergy Clin Immunol Pract. 2020 Sep;8(8):2487-2488. doi: 10.1016/j.jaip.2020.06.008. Epub 2020 Jun 22. PMID: 32585410.
- Biologic and maintenance systemic corticosteroid therapy among US subspecialist-treated patients with severe asthma. Moore WC, Panettieri RA Jr, Trevor J, Ledford DK, Lugogo N, Soong W, Chipps BE, Carr W, Belton L, Gandhi H, Trudo F, Ambrose CS. Ann Allergy Asthma Immunol. 2020 Sep;125(3):294-303.e1. doi: 10.1016/j.anai.2020.04.004. Epub 2020 Apr 15. PMID: 32304877.
- TENOR Revisited. Panettieri RA Jr, Chupp G. J Allergy Clin Immunol Pract. 2020 Jul-Aug;8(7):2254-2255. doi: 10.1016/j.jaip.2020.04.044. PMID: 32620435.
- ARRIVE 2.0 and the British Journal of Pharmacology: Updated guidance for 2020. Lilley E, Stanford SC, Kendall DE, Alexander SPH, Cirino G, Docherty JR, George CH, Insel PA, Izzo AA, Ji Y, Panettieri RA, Sobey CG, Stefanska B, Stephens G, Teixeira M, Ahluwalia A. Br J Pharmacol. 2020 Aug;177(16):3611-3616. doi: 10.1111/bph.15178. Epub 2020 Jul 14. PMID: 32662875.
- Detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Is Comparable in Clinical Samples Preserved in Saline or Viral Transport Medium. Radbel J, Jagpal S, Roy J, Brooks A, Tischfield J, Sheldon M, Bixby C, Witt D, Gennaro ML, Horton DB, Barrett ES, Carson JL, Panettieri RA Jr, Blaser MJ. J Mol Diagn. 2020 Jul;22(7):871-875. doi: 10.1016/j.jmoldx.2020.04.209. Epub 2020 May 13. PMID: 32405270.
- The CHRONICLE Study of US Adults with Subspecialist-Treated Severe Asthma: Objectives, Design, and Initial Results. Ambrose CS, Chipps BE, Moore WC, Soong W, Trevor J, Ledford DK, Carr WW, Lugogo N, Trudo F, Tran TN, Panettieri RA Jr. Pragmat Obs Res. 2020 Jul 16;11:77-90. doi: 10.2147/POR.S251120. eCollection 2020. PMID: 32765156.
- Impact of a Respiratory Disease Young Investigators’ Forum on the Career Development of Physician-Scientists. Panettieri RA Jr, Kolls JK, Lazarus S, Corder S, Harshman A, Langmack E, Petrache I. ATS Sch. 2020 Jun 16;1(3):243-259. doi: 10.34197/ats-scholar.2019-0018OC. PMID: 33870292.
- The COVID-19 pandemic and research shutdown: staying safe and productive. Omary MB, Eswaraka J, Kimball SD, Moghe PV, Panettieri RA Jr, Scotto KW. J Clin Invest. 2020 Jun 1;130(6):2745-2748. doi: 10.1172/JCI138646. PMID: 32243259.
- Role of CD38/cADPR signaling in obstructive pulmonary diseases Guedes AG, Dileepan M,Jude JA, Deshpande DA, Walseth TF, Kannan MS. Curr Opin Pharmacol. 2020 May 29;51:29-33. Online ahead of print.
- Important lessons learned from studies on the pharmacology of glucocorticoids in human airway smooth muscle cells: Too much of a good thing may be a problem. Amrani Y, Panettieri RA, Ramos-Ramírez P, Schaafsma D, Kaczmarek K, Tliba O. Pharmacol Ther. 2020 May 27:107589. Epub ahead of print.
- CD2 Regulates Pathogenesis of Asthma Induced by House Dust Mice Extract. Hashem T, Kammala AK, Thaxton K, Griffin RM, Mullany K, Panettieri RA Jr, Subramanian H, Das R. Front Immunol. 2020 May 12;11:881. doi: 10.3389/fimmu.2020.00881. eCollection 2020. PMID: 32477356.
- Prevalence of SARS-CoV-2 infection in previously undiagnosed health care workers at the onset of the U.S. COVID-19 epidemic. Barrett ES, Horton DB, Roy J, Gennaro ML, Brooks A, Tischfield J, Greenberg P, Andrews T, Jagpal S, Reilly N, Blaser MJ, Carson JL, Panettieri RA Jr. medRxiv. 2020 Apr 24:2020.04.20.20072470. doi: 10.1101/2020.04.20.20072470. Preprint. PMID: 32511600.
- Rhinovirus C15 Induces Airway Hyperresponsiveness via Calcium Mobilization in Airway Smooth Muscle Parikh V, Scala J, Patel R, Corbi C, Lo D, Bochkov YA, Kennedy JL, Kurten RC, Liggett SB, Gern JE, Koziol-White CJ. . Am J Respir Cell Mol Biol. 2020 Mar;62(3):310-318. doi: 10.1165/rcmb.2019-0004OC. PMID: 31533004.
- RGS4 promotes allergen- and aspirin-associated airway hyperresponsiveness by inhibiting PGE2 biosynthesis Wong GS, Redes JL, Balenga N, McCullough M, Fuentes N, Gokhale A, Koziol-White C,Jude JA, Madigan LA, Chan EC, Jester WH, Biardel S, Flamand N, Panettieri RA Jr, Druey KM. . J Allergy Clin Immunol. 2020 Mar 19:S0091-6749(20)30372-9. Online ahead of print.
- Glucocorticoids rapidly activate cAMP production via G<sub>αs</sub> to initiate non-genomic signaling that contributes to one-third of their canonical genomic effects Nuñez FJ, Johnstone TB, Corpuz ML, Kazarian AG, Mohajer NN, Tliba O, Panettieri RA Jr, Koziol-White C, Roosan MR, Ostrom RS. FASEB J. 2020 Feb;34(2):2882-2895. Epub 2019 Dec 27.
- Onset of Effect, Changes in Airflow Obstruction and Lung Volume, and Health-Related Quality of Life Improvements with Benralizumab for Patients with Severe Eosinophilic Asthma: Phase IIIb Randomized, Controlled Trial (SOLANA). Panettieri RA Jr, Welte T, Shenoy KV, Korn S, Jandl M, Kerwin EM, Feijoo R, Barker P, Olsson RF, Martin UJ; SOLANA Study Investigators. J Asthma Allergy. 2020 Feb 17;13:115-126. doi: 10.2147/JAA.S240044. eCollection 2020. PMID: 32110060.
- Lipid-laden macrophages as biomarkers of vaping-associated lung injury. Guerrini V, Panettieri RA Jr, Gennaro ML. Lancet Respir Med. 2020 Feb;8(2):e6. doi: 10.1016/S2213-2600(19)30476-X. PMID: 32035068.
- Budesonide enhances agonist-induced bronchodilation in human small airways by increasing cAMP production in airway smooth muscle Koziol-White C, Johnstone TB, Corpuz ML, Cao G, Orfanos S, Parikh V, Deeney B, Tliba O, Ostrom RS, Dainty I, Panettieri RA Jr. Am J Physiol Lung Cell Mol Physiol. 2020 Feb 1;318(2):L345-L355. Epub 2019 Nov 20.
- Soluble Guanylate Cyclase Agonists Induce Bronchodilation in Human Small Airways Koziol-White CJ, Ghosh A, Sandner P, Erzurum SE, Stuehr DJ, Panettieri RA Jr. . Am J Respir Cell Mol Biol. 2020 Jan;62(1):43-48. doi: 10.1165/rcmb.2019-0001OC. PMID: 31340135.