2016 Publications
Defining an olfactory receptor function in airway smooth muscle cells. Aisenberg WH, Huang J, Zhu W, Rajkumar P, Cruz R, Santhanam L, Natarajan N, Yong HM, De Santiago B, Oh JJ, Yoon AR, Panettieri RA, Homann O, Sullivan JK, Liggett SB, Pluznick JL, An SS. Sci Rep. 2016 Dec 1;6:38231. doi: 10.1038/srep38231. PMID: 27905542 .
Inhibition of spleen tyrosine kinase attenuates IgE-mediated airway contraction and mediator release in human precision cut lung slices. Koziol-White CJ, Jia Y, Baltus GA, Cooper PR, Zaller DM, Crackower MA, Sirkowski EE, Smock S, Northrup AB, Himes BE, Alves SE, Panettieri RA Jr. Br J Pharmacol. 2016 Nov;173(21):3080-3087. doi: 10.1111/bph.13550. Epub 2016 Oct 5. PMID: 27417329 .
Formaldehyde Induces Rho-Associated Kinase Activity to Evoke Airway Hyperresponsiveness. Jude J, Koziol-White C, Scala J, Yoo E, Jester W, Maute C, Dalton P, Panettieri R Jr. Am J Respir Cell Mol Biol. 2016 Oct;55(4):542-553. doi: 10.1165/rcmb.2015-0254OC. PMID: 27149505 .
Inhibition of PI3K promotes dilation of human small airways in a rho kinase-dependent manner. Koziol-White CJ, Yoo EJ, Cao G, Zhang J, Papanikolaou E, Pushkarsky I, Andrews A, Himes BE, Damoiseaux RD, Liggett SB, Di Carlo D, Kurten RC, Panettieri RA Jr. Br J Pharmacol. 2016 Sep;173(18):2726-38. doi: 10.1111/bph.13542. Epub 2016 Aug 3. PMID: 27352269 .
Upregulation of RGS2: a new mechanism for pirfenidone amelioration of pulmonary fibrosis. Xie Y, Jiang H, Zhang Q, Mehrotra S, Abel PW, Toews ML, Wolff DW, Rennard S, Panettieri RA Jr, Casale TB, Tu Y. Respir Res. 2016 Aug 22;17(1):103. doi: 10.1186/s12931-016-0418-4. PMID: 27549302 .
Neutrophilic and Pauci-immune Phenotypes in Severe Asthma. Panettieri RA Jr. Immunol Allergy Clin North Am. 2016 Aug;36(3):569-79. doi: 10.1016/j.iac.2016.03.007. Epub 2016 Jun 2. PMID: 27401627 .
Glucocorticoid and TNF signaling converge at A20 (TNFAIP3) to repress airway smooth muscle cytokine expression. Sasse SK, Altonsy MO, Kadiyala V, Cao G, Panettieri RA Jr, Gerber AN. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L421-32. doi: 10.1152/ajplung.00179.2016. Epub 2016 Jul 1. PMID: 27371733.
Directed migration of cancer cells guided by the graded texture of the underlying matrix. Park J, Kim DH, Kim HN, Wang CJ, Kwak MK, Hur E, Suh KY, An SS, Levchenko A. Nat Mater. 2016 Jul;15(7):792-801. doi: 10.1038/nmat4586. Epub 2016 Mar 14. PMID: 26974411.
An inflammation-independent contraction mechanophenotype of airway smooth muscle in asthma. An SS, Mitzner W, Tang WY, Ahn K, Yoon AR, Huang J, Kilic O, Yong HM, Fahey JW, Kumar S, Biswal S, Holgate ST, Panettieri RA Jr, Solway J, Liggett SB. J Allergy Clin Immunol. 2016 Jul;138(1):294-297.e4. doi: 10.1016/j.jaci.2015.12.1315. Epub 2016 Feb 28. PMID: 26936804 .
Epithelium-generated neuropeptide Y induces smooth muscle contraction to promote airway hyperresponsiveness. Li S, Koziol-White C, Jude J, Jiang M, Zhao H, Cao G, Yoo E, Jester W, Morley MP, Zhou S, Wang Y, Lu MM, Panettieri RA Jr, Morrisey EE. J Clin Invest. 2016 May 2;126(5):1978-82. doi: 10.1172/JCI81389. Epub 2016 Apr 18. PMID: 27088802 .
Soluble guanylate cyclase as an alternative target for bronchodilator therapy in asthma. Ghosh A, Koziol-White CJ, Asosingh K, Cheng G, Ruple L, Groneberg D, Friebe A, Comhair SA, Stasch JP, Panettieri RA Jr, Aronica MA, Erzurum SC, Stuehr DJ. Proc Natl Acad Sci U S A. 2016 Apr 26;113(17):E2355-62. doi: 10.1073/pnas.1524398113. Epub 2016 Apr 11. PMID: 27071111 .
MicroRNA Mediated Chemokine Responses in Human Airway Smooth Muscle Cells. Dileepan M, Sarver AE, Rao SP, Panettieri RA Jr, Subramanian S, Kannan MS. PLoS One. 2016 Mar 21;11(3):e0150842. doi: 10.1371/journal.pone.0150842. eCollection 2016. PMID: 26998837 .
Interdicting Gq Activation in Airway Disease by Receptor-Dependent and Receptor-Independent Mechanisms. Carr R 3rd, Koziol-White C, Zhang J, Lam H, An SS, Tall GG, Panettieri RA Jr, Benovic JL. Mol Pharmacol. 2016 Jan;89(1):94-104. doi: 10.1124/mol.115.100339. Epub 2015 Oct 13. PMID: 26464325.