Pregnancy weight and biochemical markers measured in blood from women with gestational diabetes mellitus (GDM) were related to increased risk of poor pregnancy outcomes, suggesting a new direction for precision diagnostics, according to researchers. The study led by Ellen C. Francis, an assistant professor in the Department of Biostatistics and Epidemiology at Rutgers School of Public Health, and published in Nature Communications Medicine, evaluated the diagnostic value of these markers before or at the time of screening for GDM, a type of diabetes that can develop during pregnancy.

“Although we found that obesity is a risk factor for offspring born larger for their gestational age, evidence suggests that the metabolic alterations that accompany obesity increase the risk of adverse outcomes,” said Francis. GDM, characterized by elevated blood sugar (glucose) levels during pregnancy, is the most common metabolic condition among pregnant women and poses risks to both mother and child. While standard treatments are applied, clinical outcomes can differ among individuals. To read the full story.