RITMS News & Announcements


NIH Clinical Center releases dataset of 32,000 CT images.


Read Drs. Cao & Panettieri's article Glucocorticoid and TNF signaling converge at A20 (TNFAIP3) to repress airway smooth muscle cytokine expression.

Read Dr. Koziol-White et al. article Inhibition of Phosphoinositide 3-Kinase (PI3K) promotes dilation of human small airways in a Rho kinase-dependent manner.


Read Dr. Jude et al. article Formaldehyde induces Rho-associated kinase activity to evoke airway hyperresponsiveness.


ATS 2018 Posters

Christie Ojiaku | TGF-β1 Mediates HASM Cell Hyporesponsiveness to β2-Agonist-Induced Relaxation

Brian Deeney | Epinephrine Induces Human Airway Smooth Muscle Contraction Through the Alpha-1 Adrenergic Receptor After Beta-2 Adrenergic Receptor Desensitization

Cynthia Koziol-White | Rhinovirus C15, but not A16, induces airway hyperresponsiveness in human small airways and airway smooth muscle (HASM) through modulation of calcium and actin dynamics

Joseph Jude | Airway Smooth Muscle Function is Altered in Obesity to Enhance Airway Responsiveness to Carbachol


ATS 2017 Posters

Christie Ojiaku | TGF - ß1 Induces HASM Cell Shortening and Airway Hyperresponsiveness Through a Smad3-Dependent Signaling Pathway

Edwin Yoo | G a12 Facilitates Methacholine -Induced Shortening in Human Airway Smooth Muscle By Modulating Phosphoinositide 3-Kinase-Mediated Activation In A RhoA-Dependent Manner

Cynthia Koziol-White | Rhinovirus strains differentially affect airway hyper-reactivity (AHR) in a model of human precision cut lung slices ( hPCLS )

Joseph Jude | 2,4-Dichloro-1-nitrobenzene (DCNB) Modulates Pro-contractile Signaling in Human Airway Smooth Muscle (HASM) Cells

ATS 2016 Posters

Christie Ojiaku | TGF-ß1 Evokes Human Airway Smooth Muscle Shortening and Hyperresponsiveness: A New Job Description?

Edwin Yoo | Elevated Histone H3K27 Methylation Mediates Intrinsic Hypercontractility in Human Airway Smooth Muscle Cells From Subjects with Fatal Asthma

Cynthia Koziol-White | A narrow spectrum kinase inhibitor, RV1729, induces bronchodilation of human small airways and rescues agonist-induced desensitization of the ß2adrenoreceptor(ß2AR)

Joseph Jude | Toxicants, salicylic acid and toluene diisocyanate, enhance carbachol-induced bronchoconstrictionin human precision-cut lung slices (hPCLS)


Reynold A. Panettieri, Jr. named Inaugural Director of the Clinical and Translational Science Institute


Rutgers Makes Major Commitment to Translational Science
Reynold Panettieri will develop the university’s clinical and translational science institute.


Drilling and Public Health: A Day of Discovery-Dr. Panettieri 

https://www.youtube.com/watch?v=02uQKDsQros


Scientists Identify Biological Pathway That Could Explain Why Asthma Therapies Are Ineffective


Read Drs. Koziol-White, Jude et al. article An epithelial-smooth muscle paracrine pathway that induces asthma through ectopic expression of neuropeptide-Y.


COPD Recidivism


Read Drs. Koziol-White & Panettieri's article Soluble guanylate cyclase as an alternative target for bronchodilator therapy in asthma.


Chronic Obstructive Pulmonary Disease, Asthma, or Both


Read Dr. Panettieri's article MicroRNA mediated chemokine responses in human airway smooth muscle cells.


DHA Health Risk: Potential Lung Complications


Read Dr. Panettieri's article An inflammation-independent contraction mechanophenotype of airway smooth muscle in asthma.


Read Dr. Panettieri's article Bronchial Thermoplasty: Targeting Structural Cells in Severe Persistent Asthma.  


Read Drs. Koziol-White & Panettieri's article Interdicting Gq Activation in Airway Disease by Receptor-Dependent and Receptor-Independent Mechanisms.


Read Drs. Koziol-White & Panettieri's article Immunostimulatory defective viral genomes from respiratory syncytial virus promote a strong innate antiviral response during infection in mice and humans. 


Introduction from Dr. Panettieri


Read Dr. Panettieri's article in Penn Medicine magazine, Fracking and Public Health: Finding the Best Balance.   


Read Dr. Panettieri's article Unconventional gas and oil drilling is associated with increased hospital utilization rates. 

Read Dr. Panettieri's article Functional capacity, health status and inflammatory biomarker profile in a cohort of patients with COPD.

Read Dr. Panettieri's article Bronchodilators, receptors and cross-talk: Together is better?

Please listen to Dr. Panettieri's interview on WPEL with Larry Souder on hydrofracking.  https://soundcloud.com/user-8197160…/special-assignment-wpel

Read Dr. Panettieri's article MicroRNA-203 negatively regulates c-Abl, ERK1/2 phosphorylation, and proliferation in smooth muscle cells. 


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