In Vivo Research Services (IVRS)

The mission of the IVRS is to provide centralized high quality, cost-effective research services to both academic and industry clients. Rutgers has a wealth of experience, capabilities and models that are routinely used to answer critical in vivo research questions. IVRS provide a comprehensive program of animal care including consultation, experimental design, protocol preparation, a duly constituted animal care and use committee, occupational health and laboratory safety, BSL3 in vivo biohazard research, and full-time veterinary care. Rutgers offers competitive fee-for-service pricing, confidentiality, accuracy, and rapid service. Our team is dedicated to humane animal research.

What do we do for Rutgers Faculty?

Provide technical services for:

–faculty who never have done or do not have knowledge of in vivo studies
–faculty who are short of staff
–faculty who need experts to perform specialized procedures or surgeries

Types of technical services, fee-for-service basis

–Technical assistant on per hour basis
–Performing entire research project

In vivo model consultation
Hands-on training (surgeries or procedures)
Letters of support for grants
Co-Investigator for federal grants
IVRS offer discounted fees for biological tests

IVRS Research Services

Fee-for-service basis
Competitive pricing
Flexibility
Confidentiality
Accuracy
Rapid service
IVRS veterinary and technical staff have capabilities and expertise to perform broad range of in vivo research
IVRS offers “one stop shop” services collaborating with other core facilities

Examples of Services Offered

Training: Routine or specialized procedures and surgeries (CMR staff usually perform the routine procedure trainings)
Non-surgical procedures
Routine procedures: injections, bleedings, fluid collection
Specialized procedures: intrathecal (IT), intranasal (IN), intra-orbital (IO), Intraventricular (ICV), Subrenal capsule, intra-mammary gland, intra-cardiac, intravitreal injections
Surgical models: TBI model, splenectomy, hepatectomy, thymectomy, vasectomy, ovariectomy, vagotomy, pyloroplasty, double carotid occlusion. Cannulation jugular vein or carotid artery, bile duct, intrathecal, intracerebroventricle (IVC), lymph duct splenectomy, hepatectomy, thymectomy, pyloroplasty, double carotid occlusion, stereotactic surgeries
Surgical and non-surgical model development
IVRS staff will assist you to develop animal models
Preclinical studies: PK, PD and ADME studies
Xenograft studies: mouse strains selection, performing studies (tumor cells injections,PDX, orthotopic and surgical metastatic models)
Consultation: animal models selection, grant preparation, experimental design

Rodent Research Equipment

CODA® noninvasive blood pressure monitor: measures six blood pressure parameters: systolic, diastolic, and mean BP, heart rate, tail blood volume and blood flow
Physio Suite® peri-op monitoring system: monitors for pulse oximetry, heart rate, O2, end-tidal CO2
High throughput inhalation anesthetic machines
Stereotaxic device for Mice & Rats
Stereo microscope for microsurgery with monitor and camera

IVRS Laboratory Diagnostic Devices

Heska Element DC5X ® Blood Chemistry Analyzer measures: BUN, CREA, ALP, ALT, PHOS, GGT, TBIL, AS, GLU, TP, ALB, Ca, Mg, NH3, TRIG, LIP, AMY, CK, URIC, CHOL, LDH, Electrolytes (Na+, K+, Cl-)
HESKA HT5®
Hematology analyzer
White blood cell (WBC) total WBC number and % of neutrophils, lymphocytes, monocytes, eosinophils and basophils
Red blood cell (RBC), hemoglobin, hematocrit, platelets, MCV, MCH, MCHC, MPV, Red Blood Cell Distribution (RDW-CV)

Large Animal Facility at Newark

Pig, sheep, dog, rabbit

1.Animal Preparation room
2.Surgeon Preparation room
3.Two Operating suites
4.Two Large Animal recovery rooms

Large Animal Surgery Equipment

1.Anesthesia machines , 3 units
2.Fluoroscopy machine, 1 unit
3.Operating tables (3 tables)
4.EPOC, Blood Gas & Electrolyte Analyzer
5.Miscellaneous surgical support equipment

Service Fees

IVRS Technical staff $65/hour
Veterinarian $100/hour
Please refer to this link for additional charges: http://orad.rutgers.edu/veterinary-and-veterinary-technical-services