Gaoyuan Cao, M.D., M.S.
Senior Research Investigator
Rutgers Institute for Translational Medicine and Science
Child Health Institute of New Jersey
Rutgers, The State University of New Jersey
89 French Street
New Brunswick, NJ 08901
Fax: (732) 235-7178
gaoyuan.cao@rutgers.edu
Education
B.M.in clinical medicine, West China University of Medical Sciences, Sichuan University, Chengdu, China
M.S. in Medical Science, West China University of Medical Sciences, Sichuan University, Chengdu, China
Dr. Cao has more than twenty years of experience performing biomedical research and teaching with an emphasis in histology, embryology and neurobiology. Before joining the Rutgers Institute for Translational Medicine and Science in 2016, Dr. Cao had previously served as a senior research investigator at the Airways Biology Initiative at the University of Pennsylvania. Since joining he has developed a several different protocols for isolating human airway smooth muscles cells, fibroblasts and macrophages, and mouse lung blood vessels and endothelial cells. His current research interests include beta-2AR agonist and beta-2AR desensitization and their use in the treatment of asthma and the effects of the micro-environmental factors on airway smooth muscle cells contraction and relaxation in asthma.
Selected Publications
- MAIT cell deficiency exacerbates neuroinflammation in P301S human tau transgenic mice. Zhang Y, Yang Z, Jiang N, Tan X, Jiang P, Cao G, Yang Q.J Neuroinflammation. 2025 Mar 20;22(1):90. doi: 10.1186/s12974-025-03413-7.PMID: 40114233
- Distinct mural cells and fibroblasts promote pathogenic plasma cell accumulation in idiopathic pulmonary fibrosis. Yang Z, Cao G, Tan X, Orfanos S, Jude J, Barbet G, An SS, Jiang D, Panettieri RA Jr, Yang Q.Eur Respir J. 2025 Feb 20:2401114. doi: 10.1183/13993003.01114-2024. Online ahead of print.PMID: 39978854
- Serum cAMP levels are increased in patients with asthma. An SS, Cao G, Ahn K, Lee J, Jung DY, Denlinger L, Fahy J, Israel E, Moore W, Phillips B, Mauger D, Wenzel S, Panettieri RA Jr. J Clin Invest. 2025 Jan 7:e186937. PMID: 39774028 DOI: 10.1172/JCI186937
- Correction: Precision cut lung slices: an integrated ex vivo model for studying lung physiology, pharmacology, disease pathogenesis and drug discovery. Koziol-White C, Gebski E, Cao G, Panettieri RA Jr.Respir Res. 2025 Jan 27;26(1):42. doi: 10.1186/s12931-024-03085-6.PMID: 39871277
- VRAC Complex Modulates Mechano-Electrical Signal Responses in Human Airway Smooth Muscle Shortening. Woo J, Cao G, Karmacharya N, Lee J, Lee J, Duru KC, McClenaghan C, An SS, Panettieri RA Jr, Jude JA.Am J Respir Cell Mol Biol. 2024 Oct 29. doi: 10.1165/rcmb.2024-0160OC. Online ahead of print.PMID: 39470451
- Identification of a β-arrestin-biased negative allosteric modulator for the β2-adrenergic receptor. Proc Natl Acad Sci U S A. 2023 Aug;120(31):e2302668120. doi: 10.1073/pnas.2302668120. Epub 2023 Jul 25.PMID: 37490535
- Adventitial stromal cells and myofibroblasts recruit pro- and anti-inflammatory immune cells in allergic airway inflammation. Allergy. 2023 Nov;78(11):2994-2997. doi: 10.1111/all.15766. Epub 2023 May 20.PMID: 37171245
- Rhinovirus C15 Attenuates Relaxation and cAMP Production in Human Airways and Smooth Muscle. Am J Respir Cell Mol Biol. 2023 Aug;69(2):172-181. doi: 10.1165/rcmb.2021-0526OC.PMID: 37098126
- Mucosal-associated invariant T cells restrict reactive oxidative damage and preserve meningeal barrier integrity and cognitive function. Zhang Y, Bailey JT, Xu E, Singh K, Lavaert M, Link VM, D’Souza S, Hafiz A, Cao J, Cao G, Sant’Angelo DB, Sun W, Belkaid Y, Bhandoola A, McGavern DB, Yang Q.Nat Immunol. 2022 Dec;23(12):1714-1725. doi: 10.1038/s41590-022-01349-1. Epub 2022 Nov 21.PMID: 36411380
- Starving a Cell Promotes Airway Smooth Muscle Relaxation: Inhibition of Glycolysis Attenuates Excitation-Contraction Coupling. Xu S, Karmacharya N, Woo J, Cao G, Guo C, Gow A, Panettieri RA Jr, Jude JA.Am J Respir Cell Mol Biol. 2023 Jan;68(1):39-48. doi: 10.1165/rcmb.2021-0495OC.PMID: 36227725