RITMS News & Announcements

Read Drs. Cao & Panettieri's article Glucocorticoid and TNF signaling converge at A20 (TNFAIP3) to repress airway smooth muscle cytokine expression.

Read Dr. Koziol-White et al. article Inhibition of Phosphoinositide 3-Kinase (PI3K) promotes dilation of human small airways in a Rho kinase-dependent manner.

Read Dr. Jude et al. article Formaldehyde induces Rho-associated kinase activity to evoke airway hyperresponsiveness.

ATS 2017 Posters

Christie Ojiaku | TGF - ß1 Induces HASM Cell Shortening and Airway Hyperresponsiveness Through a Smad3-Dependent Signaling Pathway

Edwin Yoo | G a12 Facilitates Methacholine -Induced Shortening in Human Airway Smooth Muscle By Modulating Phosphoinositide 3-Kinase-Mediated Activation In A RhoA-Dependent Manner

Cynthia Koziol-White | Rhinovirus strains differentially affect airway hyper-reactivity (AHR) in a model of human precision cut lung slices ( hPCLS )

Joseph Jude | 2,4-Dichloro-1-nitrobenzene (DCNB) Modulates Pro-contractile Signaling in Human Airway Smooth Muscle (HASM) Cells

ATS 2016 Posters

Christie Ojiaku | TGF-ß1 Evokes Human Airway Smooth Muscle Shortening and Hyperresponsiveness: A New Job Description?

Edwin Yoo | Elevated Histone H3K27 Methylation Mediates Intrinsic Hypercontractility in Human Airway Smooth Muscle Cells From Subjects with Fatal Asthma

Cynthia Koziol-White | A narrow spectrum kinase inhibitor, RV1729, induces bronchodilation of human small airways and rescues agonist-induced desensitization of the ß2adrenoreceptor(ß2AR)

Joseph Jude | Toxicants, salicylic acid and toluene diisocyanate, enhance carbachol-induced bronchoconstrictionin human precision-cut lung slices (hPCLS)

Reynold A. Panettieri, Jr. named Inaugural Director of the Clinical and Translational Science Institute

Rutgers Makes Major Commitment to Translational Science
Reynold Panettieri will develop the university’s clinical and translational science institute.

Drilling and Public Health: A Day of Discovery-Dr. Panettieri 


Scientists Identify Biological Pathway That Could Explain Why Asthma Therapies Are Ineffective

Read Drs. Koziol-White, Jude et al. article An epithelial-smooth muscle paracrine pathway that induces asthma through ectopic expression of neuropeptide-Y.

COPD Recidivism

Read Drs. Koziol-White & Panettieri's article Soluble guanylate cyclase as an alternative target for bronchodilator therapy in asthma.

Chronic Obstructive Pulmonary Disease, Asthma, or Both

Read Dr. Panettieri's article MicroRNA mediated chemokine responses in human airway smooth muscle cells.

DHA Health Risk: Potential Lung Complications

Read Dr. Panettieri's article An inflammation-independent contraction mechanophenotype of airway smooth muscle in asthma.

Read Dr. Panettieri's article Bronchial Thermoplasty: Targeting Structural Cells in Severe Persistent Asthma.  

Read Drs. Koziol-White & Panettieri's article Interdicting Gq Activation in Airway Disease by Receptor-Dependent and Receptor-Independent Mechanisms.

Read Drs. Koziol-White & Panettieri's article Immunostimulatory defective viral genomes from respiratory syncytial virus promote a strong innate antiviral response during infection in mice and humans. 

Introduction from Dr. Panettieri

Read Dr. Panettieri's article in Penn Medicine magazine, Fracking and Public Health: Finding the Best Balance.   

Read Dr. Panettieri's article Unconventional gas and oil drilling is associated with increased hospital utilization rates. 

Read Dr. Panettieri's article Functional capacity, health status and inflammatory biomarker profile in a cohort of patients with COPD.

Read Dr. Panettieri's article Bronchodilators, receptors and cross-talk: Together is better?

Please listen to Dr. Panettieri's interview on WPEL with Larry Souder on hydrofracking.  https://soundcloud.com/user-8197160…/special-assignment-wpel

Read Dr. Panettieri's article MicroRNA-203 negatively regulates c-Abl, ERK1/2 phosphorylation, and proliferation in smooth muscle cells. 

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