Cynthia J. Koziol-White, Ph.D.

Cindy Koziol-White

Assistant Professor
Department of Pharmacology
Robert Wood Johnson Medical School
 
Rutgers In
stitute for Translational Medicine and Science
Child Health Institute of New Jersey  
Rutgers, The State University of New Jersey 
89 French Street       

New Brunswick, NJ 08901  

Office: (732) 235-7170

Fax: (732) 235-7178

Email: cjk167@ca.rutgers.edu

Education: 

Ph.D., Molecular and Cellular Pharmacology, University of Wisconsin, Madison, WI 
B.S., Biomolecular Science, Clarkson University, Potsdam, NY

Postdoctoral Fellowship:
University of Pennsylvania, Philadelphia, PA

Dr. Koziol-White joined the laboratory in 2009 and has focused on novel human models of airway disease exacerbations using state-of-the-art molecular, imaging and cell biology methods.  Her specific projects focus on the following platforms:

Selected publications

  1. Koziol-White C.J., Jia Y., Baltus G.A., Cooper P.R., Zaller D.M., Crackower M.A., Sirkowski E.E., Smock S., Alves S.E., Panettieri R.A., Jr.Inhibition of spleen tyrosine kinase attenuates IgE-mediated bronchoconstriction and mediator release in human precision cut lung slices.  Br J Pharmacol. 2016 Jul 15.
  2. Koziol-White C.J., Yoo E.J., Cao G., Zhang J., Papanikolaou E., Puchkarsky I., Andrews A., Himes B., Damoiseaux RD., Liggett S., Di Carlo D., Kurten R., Panettieri R.A., Jr.:  Inhibition of phosphoinositide 3-kinase (PI3K) promotes bronchodilation of human small airways in a Rho kinase-dependent manner.  Br J Pharmacol. 2016 Jun 28. [Epub ahead of print]
  3. Jude J., Koziol-White C., Scala J., Jester W., Maute C., Dalton P., Panettieri R.A., Jr.:  Formaldehyde induces Rho-associated kinase activity to evoke airway hyperresponsiveness.  Am. J. Respir. Am J Respir Cell Mol Biol. 2016 May 5. [Epub ahead of print]
  4. Li S., Koziol-White C., Jude J., Jiang M., Cao G., Yoo E., Jester W., Morley M.P., Lu M.M., Panettieri R.A., Jr., Morrisey E.E.: An epithelial-smooth muscle paracrine pathway that induces asthma through ectopic expression of neuropeptide-Y.  J. Clin. Invest., 126(5):1978-82. doi: 10.1172/JCI81389. Epub 2016 Apr 18.
  5. Ghosh A., Koziol-White C.J., Asosingh K., Cheng G., Ruple L., Rodgers J., Groneberg D., Friebe A., Comhair S., Stasch J.-P., Panettieri R.A., Jr., Aronica. M.A., Erzurum S.C., Stuehr D.J.:  Soluble guanylate cyclase as an alternative target for bronchodilator therapy in asthma.  PNAS, 113(17):E2355-62.  Epub 2016 Apr 11.
  6. Carr R, Koziol-White C, Zhang J, Lam H, An SS, Tall GG, Panettieri RA, Benovic JL. Interdicting Gq Activation in Airway Disease by Receptor-Dependent and Receptor-Independent Mechanisms. Mol Pharmacol. 2015 Oct 13. [Epub ahead of print]
  7. Sun Y, Jain D, Koziol-White CJ, Genoyer E, Gilbert M, Tapia K, Panettieri RA Jr, Hodinka RL, López CB. Immunostimulatory Defective Viral Genomes from Respiratory Syncytial Virus Promote a Strong Innate Antiviral Response during Infection in Mice and Humans. PLoS Pathog. 2015 Sep 3; 11(9):e1005122. eCollection 2015 Sep.
  8. Himes BE, Koziol-White C, Johnson M, Nikolos C, Jester W, Klanderman B, Litonjua AA, Tantisira KG, Truskowski K, MacDonald K, Panettieri RA Jr, Weiss ST. Vitamin D Modulates Expression of the Airway Smooth Muscle Transcriptome in Fatal Asthma. PLoS One. 2015 Jul 24; 10(7):e0134057. eCollection 2015.
  9. Kim WK, Jain D, Sanchez MD, Koziol-White CJ, Matthews K, Ge MQ, Haczku A, Panettieri RA Jr, Frieman MB, Lopez CB. Deficiency of MDA5 Results in Exacerbated Chronic Post-Viral Lung Inflammation. Am J Respir Crit Care Med. 2014 Feb 15;189(4):437-48.
  10. Robinett KS, Koziol-White CJ, Akoluk A, An SS, Panettieri Jr RA, Liggett SB. Bitter Taste Receptor Function in Asthmatic and Nonasthmatic Human Airway Smooth Muscle Cells. Am J Respir Cell Mol Biol. 2013 Nov 12.