Joseph Jude, B.V.Sc., Ph.D.
Assistant Research Professor
Department of Pharmacology & Toxicology
Ernest Mario School of Pharmacy
Assistant Professor Department of PharmacologyRobert Wood Johnson Medical School
Rutgers Institute for Translational
Medicine and Science Child Health Institute of New Jersey Rutgers, The State University of New
Jersey 89 French Street
New Brunswick, NJ 08901
Office: (732) 235-8057
Fax: (732) 235-7178
Ph.D., University of Minnesota, St. Paul, MN
B.V.Sc., University of Peradeniya, Sri Lanka
University of Pennsylvania, Philadelphia, PA
University of Minnesota, St Paul, M
Airway smooth muscle (ASM) cells contribute to asthma pathology
through their synthetic and mechanical (contractile) functions. Dr. Jude
is interested in the molecular and cellular signaling mechanisms of ASM
cells in airway disorders such as asthma. His current research focus is
on the mechanisms of airway hypersensitivity exacerbation by
environmental pollutants like ozone. Ozone and other environmental
pollutants are associated exacerbation of clinical signs in asthmatic
- Jude J, Koziol-White C, Scala J, Yoo E, Jester W, Maute
C, Dalton P, Panettieri R Jr. Formaldehyde Induces Rho-associated Kinase
Activity to Evoke Airway Hyperresponsiveness. Am J Respir Cell Mol Biol. 2016
- Li S, Koziol-White C, Jude J, Jiang M, Zhao H, Cao G, Yoo E,
Jester W, Morley MP, Zhou S, Wang Y, Lu MM, Panettieri RA Jr, Morrisey EE.
Epithelium-generated neuropeptide Y induces smooth muscle contraction to promote
airway hyperresponsiveness. J Clin Invest. 2016 May 2; 126(5):1978-82.
- Balenga NA, Klichinsky M, Xie
Z, Chan EC, Zhao M, Jude J, Laviolette
M, Panettieri RA Jr, Druey KM. A fungal protease allergen
provokes airway hyper-responsiveness in asthma. Nat
Commun. 2015 Apr 13; 6:6763.
- Guedes AG, Jude JA,
Paulin J, Rivero-Nava L, Kita H, Lund FE, Kannan MS. Airway responsiveness in
CD38-deficient mice in allergic airway disease: studies with bone marrow
chimeras. Am J Physiol Lung Cell Mol Physiol. 2015 Mar
- Dileepan M, Jude JA,
Rao SP, Walseth TF, Panettieri RA, Subramanian S, Kannan MS. MicroRNA-708 regulates CD38
expression through signaling pathways JNK MAP kinase and PTEN/AKT in human
airway smooth muscle cells. Respir Res. 2014 Aug 31;
15(1):107. [Epub ahead of print]
- Jude JA, Dileepan M, Panettieri RA Jr, Walseth TF, Kannan MS. Altered
CD38/Cyclic ADP-Ribose Signaling Contributes to the Asthmatic Phenotype. J Allergy (Cairo). 2012;2012:289468.
- Joseph A. Jude, Mythili Dileepan, Subbaya Subramanian, Julian Solway, Reynold A.
Panettieri, Timothy F.Walseth, Mathur S. Kannan. MiR-140-3p
regulation of TNF-alpha-induced CD38 expression in human airway smooth muscle
cells. Am J Physiol Lung Cell Mol Physiol. 2012 Sep;
- Joseph A. Jude, Krishnaswamy G. Tirumurugaan, Bit Na Kang. Reynold A. Panettieri, Timothy
F. Walseth, Mathur S. Kannan. Regulation of
CD38 Expression in Human Airway Smooth Muscle Cells: Role of Class I
Phosphatidylinositol 3 Kinases. Am J Respir Cell Mol.
Biol. 2012 May 3.
- Joseph A. Jude, Reynold A. Panettieri Jr, Timothy F. Walseth and Mathur S. Kannan. TNF-alpha
regulation of CD38 expression in human airway smooth muscle: Role of MAPK
Kinases and NF-kB. Adv Exp Med Biol 2011. 691: 449-459.
- Joseph A. Jude, Julian Solway, Reynold A.
Panettieri, Timothy F. Walseth, Mathur S. Kannan. Differential
induction of CD38 expression by TNF-alpha in asthmatic airway smooth muscle
cells. Am J Physiol Lung Cell Mol Physiol. 2010, 299 (6):